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Compared to wild-type, NERNST responses to both H 2 O 2 and diamide were strongly increased in glr1 cells, suggesting that E GSH dominates the NERNST response in the cytosol of yeast cells

This raises the notion that perhaps within konzo-prone regions of sub-Saharan Africa there may be genetic variants of GPx3, or genes related to associated pathways that circulate which could alter gene expression and subsequently cause a reduction of protein abundances in these populations

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