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Not all patients will require or tolerate this dose

Monitor for unusual symptoms Pay attention to any changes in the 24-48 hours after injection

When B12 levels become problematic: High-dose supplementation (particularly doses exceeding 1,000 micrograms daily) Frequent B12 injections without medical supervision Underlying conditions affecting B12 metabolism Concurrent use of multiple B12-containing supplements The NHS does not set an upper safe limit for vitamin B12 because harmful effects from excessive intake have not been definitively established

We are living in unprecedented times but whilst all of us are in this mess together and whilst our backs are against the wall we need to see the great opportunity for change before us

We aim to make the process as straightforward as possible, ensuring you receive the care and support you need without delay

When NNMT activity is reduced, less nicotinamide is methylated and wasted, allowing NAD pools to remain higher