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Cell cultures are a useful model for establishing molecular mechanisms underlying the cellular effects of biologically active compounds, such as metabolites, signaling molecules, drugs etc

While we believe in embracing our natural features, we also think you should do what feels right for you and your body

FPN is regulated by hepcidin, a hepatic-secreted peptide hormone, which promotes the internalization and degradation of FPN [74]

The hepatotoxic effects of APAP are primarily mediated by its bioactivation to the reactive metabolite NAPQI via CYP2E1

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