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H&E of the tumorous tissue of the animal model treated with NP4 showed high amounts of cell death and nuclear fragmentation (Fig

Li X, Liang J, Qu L, Liu S, Qin A, Liu H, et al

This finding has important implications for the design of future clinical trials in AHF patients, as the selection of appropriate patients may increase the chances of detecting the real efficacy of new treatments

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It is approximately 44,000 times more selective for DPP-8 dpp-4 than DPP-8 and about 10,000 times more selective than DPP-9, which results in Linagliptin primarily targeting DPP-4 with very little effect on DPP-8 or DPP-9 [30]

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