En 1958, Fritz descubri que la L-carnitina desempeaba un papel crucial en la oxidacin de los cidos grasos de cadena larga en el tejido cardaco y muscular, pudiendo aumentar la tasa metablica de la Beta-oxidacin de las grasas y acelerar el consumo de grasas por parte de las clulas (Mitocondria)
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GLP-1RA can reduce ectopic fat through appetite suppression and weight loss, improving insulin sensitivity, enhancing fatty acid oxidation, through anti-inflammatory and directly through tissue-specific action via GLP-1 receptors in liver, heart, pancreas and brain [72,73,74,75]
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When considering the use of Tirzepatide, patients must be aware of certain risks associated with the medication, including increased chances of pancreatitis, potential hypoglycemia, and thyroid tumors
For most, this is a minor cardiovascular response, but for sensitive individuals, it feels like a racing heart