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The cell can become distorted and unstable if it doesn't get enough of the vitamin
TCB II: 4247kDa protein Essential protein in the delivery of vitamin B12 to cells and tissues The production site of TCB II is primarily hepatocytic, and secondarily endothelial, monocytic and intestinal Functions of vitamin B12: B12 acts as a cofactor for two key enzymatic reactions: Methionine Synthase (cytoplasm): Converts homocysteine methionine Requires methylcobalamin Supports DNA synthesis via the folate cycle (regenerates tetrahydrofolate) Methylmalonyl-CoA Mutase (mitochondria): Converts methylmalonyl-CoA succinyl-CoA Requires adenosylcobalamin Involved in fatty acid and amino acid metabolism Elevated vitamin B12 (hypervitaminemia B12) While vitamin B12 deficiency is commonly discussed, elevated serum B12 (hypercobalaminemia) is less common and often overlooked or misinterpreted
doi: 10.1093/advances/nmy063 187 BiswasSBanerjeeER
B12 shots are a quick and easy way to increase your vitamin levels
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Mol Endocrinol (2003) 17(11):221127.10.1210/me.2003-0256 64 FrankSJYiWZhaoYGoldsmithJFGillilandGJiangJet alRegions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
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