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Probiotic Lactobacillus rhamnosus GG promotes mouse gut microbiota diversity and T cell differentiation

A 2023 systematic review and meta-analysis of 82 RCTs (10,332 patients) examined probiotics for IBS symptoms, and for abdominal bloating or distension reported only very low certainty in the evidence for a benefit, with some specific combination probiotics and Bacillus strains showing potential signals.[5] Certainty grading reflects how confident the analysis is in the effect estimate

Epub 2019 Apr 2

TB-500 has the stronger evidence for wound healing and cardiac tissue repair

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These gut-focused mechanisms are particularly relevant for autoimmune diseases with gastrointestinal involvement, but researchers increasingly believe that gut barrier integrity influences autoimmune activity far beyond the digestive tract