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Mutations in the MTHFR genes (specifically 677 and 1298) can disrupt this cycle

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Malabsorption due to digestive disorders, such as Crohns disease or celiac disease, can also lead to vitamin B12 deficiency

Unfortunately, that means you lose a significant amount of the nutrients in the pill before they can provide any benefits to your body

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Human Chorionic Gonadotropin. Cleveland Clinic , my.clevelandclinic.org/health/articles/22489-human-chorionic-gonadotropin