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Conjugation of glutathione and other thiols with bioreductively activated mitomycin C
To measure average proteome height, we labeled the N-terminus of cell surface proteins using an amine-reactive biotin (NHS-Biotin) at low pH (pH 6.5)(50)
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While tirzepatide alone carries a lower intrinsic hypoglycemia risk compared to these agents due to its glucose-dependent mechanism, alcohol's suppression of hepatic glucose production can precipitate dangerous blood sugar drops
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