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[9] [11] [17] [49] Administration of levothyroxine resulting in suppressed serum thyrotropin (TSH) concentrations has been associated with bone loss and the potential increased risk for osteopenia and the premature development of osteoporosis

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calcium ipodate) decrease T4 production, an effect presumably mediated by release of iodine as the drug is metabolized, and also acutely inhibit peripheral T4 to T3 conversion (8)