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One of the most serious conditions identified is non-arteritic anterior ischemic optic neuropathy (NAION), which causes sudden vision loss

Additional considerations include diabetic retinopathy status (semaglutide may worsen retinopathy in some patients with pre-existing disease, particularly with rapid A1c improvement), history of pancreatitis (use GLP-1 agents with caution), and upcoming surgical procedures (discuss with your surgical/anesthesia team due to effects on gastric emptying)

10.1111/j.1468-3083.2012.04706.x

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As with any medication, Semaglutide can have side effects, although they are generally well-tolerated