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Although effective, these medications often present such side effects as skin rashes, fever, arthralgia, liver toxicity, and agranulocytosisan extreme decline in white blood cell count-that preclude their long-term use in certain patients (Mishra et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Sekikawa T., Kizawa Y., Li Y., Takara T

7.5 Co-culture-on-chip of multiple autologous cells: a challenge toward multi-tissue aOoC Another major challenge in the development of multi-tissue aOoC platforms lies in the integration and functional synchronization of different autologous cell types within a shared microphysiological environment

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Ipamorelin is a synthetic pentapeptide GH secretagogue (Aib-His-D-2-Nal-D-Phe-Lys-NH) and selective GHS-R1a (ghrelin receptor) agonist, distinguished within the GHRP class by its exceptional selectivity for GH release with minimal co-stimulation of cortisol, prolactin, or ACTH