The BBB, composed of tightly joined endothelial cells, astrocytic end-feet, and pericytes, serves as a selective barrier that regulates the passage of substances from the bloodstream into the brain parenchyma (Oldendorf, 1971), while macromolecules such as transferrin and insulin use endothelial receptor-mediated transport (Nance et al., 2022)
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& Mobley, H
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With oral Wegovy, it must be taken on an empty stomach with a small sip of water, followed by a 30-minute wait before eating, drinking, or taking other medications