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If you added 2 mL instead of 1 mL to a 5 mg vial, your concentration is 2.5 mg/mL instead of 5 mg/mL, and you need to draw twice as many units to get the same dose

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These mtROS suppress autophagic clearance by oxidatively inactivating the IRS-1/PI3K pathway [413], while simultaneously activating HIF-1 to promote glycolysis, creating a nutrient-rich microenvironment for MTB