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typically peaks in first 48 weeks then subsides Diarrhoea, vomiting, abdominal pain, constipation Decreased appetite contributes to the weight loss benefit Dyspepsia, abdominal distension, eructation (belching), flatulence COMMON SIDE EFFECTS (1 in 10 to 1 in 100 patients): Hypoglycaemia (low blood sugar): LOW RISK when used as monotherapy

It's only aspirin, which has been around for more than a century

Clinical phenotyping remains equally informative

Foods rich in vitamin B12 and folate, such as eggs, dairy products, and fortified cereals, are also important

GCD mostly is acquired but congenital forms have also been described