If your insurance covers GLP-1 medications, a provider that works with insurance may be more cost-effective
HK-2 cells:human kidney-2 cells
Though GLP-1R + cells are a relatively small subset of VSMCs, Glp1r VSM/ mice with Cre expression driven by the Myh11 promoter exhibit complete loss of immunofluorescence staining of GLP-1R in kidney sections and 95% knockdown of Glp1r mRNA expression in both renal artery and kidney (Figure 1)
Although this is an attractive approach that spurred great interest, caution should be exercised as standard dosing may be a challenge depending on individual inhalation technique
REST contributes to AKI-to-CKD transition through inducing ferroptosis in renal tubular epithelial cells
Thank you to all the patients, investigators, clinical staff, and Nanoscope team that worked hard over many years for this outcome