Your practitioner will advise on the most appropriate course of treatment following consultation
The first week, adults get 1000 mcg daily
Method Absorption Rate Advantages Disadvantages Oral pills 1.2-40% depending on intrinsic factor Convenient, widely available Poor absorption, especially with age or GI issues Sublingual Slightly better than pills No need for intrinsic factor, easy to use Still less effective than injectable forms In-clinic IM injection Nearly 100% Highly effective, professionally administered Requires clinic visits, potential travel and waiting time At home B12 injection Nearly 100% Highly effective, convenient, no travel needed Requires training, prescription, and comfort with self-injection IV infusion 100% Immediate delivery to bloodstream Most expensive, requires professional administration For many people especially those with serious deficiencies, digestive disorders, or pernicious anemia at home B12 injection offers the sweet spot of effectiveness and convenience

Tesamorelin is a synthetic GHRH analog specifically studied and FDAapproved for reducing excess abdominal fat in HIV-associated lipodystrophy, with strong data on visceral fat reduction
However, its important to assess how much of this perceived benefit is supported by evidence and what outcomes practitioners and patients can realistically expect
The traditional approach has been: But more recent evidence and updated practices across UK hospitals show that oral B12 works for many patients , if taken in the right dose and form