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The excessive accumulation of AGEs not only impacts the testicular microenvironment, but may also influence spermatogenesis by damaging spermatogonia, supporting cells, and other relevant cells [160, 219]

Figure 1 L-Cn Altered the Landscape of Gene Expression Profiles of PBMCs in Chronic HBV Infection To uncover the molecular mechanism of L-Cn that may be involved in reprogramming PBMCs after L-Cn stimulation, transcriptome profiling by RNA-Sequencing was conducted

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Kaplan M, Hammerman C, Shapiro SM