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Teratogenicity topiramate is associated with a significantly increased risk of major congenital malformations, particularly oral clefts (cleft lip and/or palate) and foetal growth restriction (small for gestational age)

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10.2147/DMSO.S528569 108 PintoL

Considering the Risks Even though the combination of semaglutide and Zofran might seem promising, its important to remember that any combination of medications should only be used under the guidance of a doctor