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The comparison group included those who used SGLT2i and did not use any GLP-1RA

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Horvath, K., et al

This indicates that differences between species may influence outcomes, despite using the same concentration range

The FDA ended broad enforcement discretion tied to shortages

The relative benefits of canagliflozin for cardiovascular outcomes were similar in individuals across the spectrum of eGFR levels (155) DECLARETIMI 58 Trial The effect of dapagliflozin on cardiovascular events has been reported (156)