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Dark spots and hyperpigmentation gradually fade, making previously uneven areas blend into the surrounding skin

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Several studies have demonstrated effectiveness of different phytoderivatives in retracting disease pathogenesis, under various in vitro and in vivo models of PD 26

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Analysis of interleukin-1 (IL-1) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization