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With more convenient dosing intervals and effectiveness for weight loss, we have seen a significant rise in the use of GLP-1 agonists

This leads to: Increased insulin secretion when glucose is present Decreased glucagon secretion Delayed gastric emptying Reduced appetite and caloric intake These combined effects help improve glycemic control and promote weight loss

Clinical trials examining both symptom scores and objective measures of esophageal healing would evaluate this potential indication

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Because GH raises glucose, patients on insulin or sulfonylureas may need glucose monitoring intensification when adding sermorelin