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Novel nanomolar potency mitochondrial complex I inhibitor IACS-1131 selectively kills OXPHOS-dependent AML cells

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For researchers evaluating these compounds, Dihexa offers more direct cognitive enhancement data and the practical advantage of oral bioavailability, but at the cost of greater mechanistic safety concerns and a compromised publication record

As such, there would seem to be no harm in supplementing a diet with reducing equivalents

It also helps to prevent the activation of tyrosinase (the enzyme that helps produce more melanin) by reducing free radicals that can activate it and cause an increase in melanin production