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Survodutide (BI 456906) is an investigational unimolecular dual agonist developed by Boehringer Ingelheim (licensed from Zealand Pharma) that activates both the glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR)

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NNMT has been explored as a target in obesity, insulin resistance, and age-related metabolic decline, supporting the rationale for translational research into body composition and performance contexts (Kannt & Pfenninger, Frontiers in Physiology )