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Lactic acidosis has been reported in approximately 32% of metformin overdose cases [see Warnings and Precautions (5.1)]

Disclosures Jos Luis Grriz has served as consultant to Boehringer Ingelheim, Mundipharma, AstraZeneca, and Novo Nordisk and has received speaker honoraria from Boehringer Ingelheim, Mundipharma, AstraZeneca, Novo Nordisk, Novartis, and Eli Lilly and Company

If its body composition changes, focus first on protein and collagen, and then consider adding metabolic support

TABLE 1 Drugs targeting HGF/c-Met in hepatocellular carcinoma patients

Reconstitute: Add 3.0 mL bacteriostatic water per 10 mg vial ~3.33 mg/mL concentration

Provider referral networks often curate vetted sources, reducing sourcing uncertainty