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Most validated objective test available

To perform the lineage tracing experiments, female Rosa-reporter mice were mated with male mice of the following genotypes: Shh-, Lgr5-GFP-, Nfatc1-, Axin2-, Gli1-, Sox9-, and Id2-CreER

For test subjects on a 2,000 g/week dosing schedule, this would equate to five 400 g injections per week or twice-daily 200 g doses

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