PE-22-28 Safety Considerations# PE-22-28's safety profile is less burdened by mechanism-specific concerns: TREK-1 channels are expressed throughout the body (brain, heart, vasculature, gastrointestinal tract), so systemic TREK-1 blockade could theoretically affect cardiovascular function, pain sensation, and gastrointestinal motility
With proper care, most patients achieve complete resolution, though patience is requiredfull recovery typically takes several months
Follow strict vegan, vegetarian, or macro-focused diets lacking natural animal proteins
Wash hands with soap and water for 20 seconds
Better vascularization means better nutrient delivery to follicles
doi: 10.1152/ajpendo.1999.277.3.E551