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Studies found that diabetic and bariatric patients taking these drugs were more likely to develop gastroparesis, which can severely impact their quality of life

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This confirms that the N-terminal modification confers the intended enzymatic stability and validates the pharmacokinetic rationale for the structural design

324 Collectively, these findings reveal that H3K9me2 demethylation by KDM3B is a conserved mechanism that drives the transcriptional activation of ATGs across malignancies

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