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Upregulated expression of PGC-1, a marker of mitochondrial biogenesis, has been observed in fibroblasts from late-stage FRDA patients, suggesting accelerated mitochondrial biogenesis [188]

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Fibroblast and collagen endpoints include: fibroblast outgrowth fibroblast migration collagen production markers collagen fibre organisation growth hormone receptor expression extracellular matrix marker changes tendon fibroblast activity This makes BPC-157 Research Peptide especially relevant to tendon, ligament and extracellular matrix research

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