Anti-nuclear antibodies in patients with procainamide-induced systemic lupus erythematosus appeared to be of the IgG class (in particular IgG1 and IgG3), whereas IgM anti-nuclear antibodies are predominant in asymptomatic users of the drug
Individuals with a positive screening test result for hepatitis B surface antigen, hepatitis C virus antibody, or HIV types 1 or 2 antibodies were excluded
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Immunnosuppressive drug therapy