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All constructs were verified by Sanger sequencing

However, the conclusion based on the present results is that an appropriate upregulation of MYH1 and downregulation of CNTN3 , as a response to a so far unknown causative factor, can protect a dog with MMVD from developing CHF

Secondary outcomes Secondary outcomes included cardiovascular mortality, all-cause mortality, non-fatal myocardial infarction (MI) and stroke, as well as hospitalisation for heart failure

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