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Gilberto Prez-Snchez, [email protected] ORCID: Norma Osnaya-Brizuela, orcid.org/0000-0003-0041-3190

This activation of the PI3K pathway could trigger Protein Kinase B (Akt), a potential enzyme within this pathway that may influence the movement of glucose transporters to the plasma membrane, potentially increasing the uptake of glucose by cells

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(Abbreviations used in this paper along with their complete names are listed in Glossary.) Figure 1 12 in the model is simulated by varying the reaction velocity of methionine synthase (MS), that is,

Subsequently, they conducted in vivo experiments to validate the tumor-suppressive role of MIEAP and found that the concurrent knockout of MIEAP and autophagy-related gene 5 (ATG5) accelerated TC development and induced the oncocytic phenotype in BRAF V600E -positive thyroid cells [169]

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