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doi:10.1159/000335607 91 Pickkers P, Darmon M, Hoste E, et al

In clinical trials like SURMOUNT-1, approximately 6% to 7% of patients reported constipation, but in real-world clinical practice, we see this number much higher

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Figure 2 shows that the biphasic PK profile obtained from the two-compartment model is consistent with intravenous data and, furthermore, that the rate of absorption as well as the maximum concentration following subcutaneous doses of different strengths were well captured by the model