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Ten-year observational follow-up of PROactive: a randomized cardiovascular outcomes trial evaluating pioglitazone in type 2 diabetes

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Specific symptoms to watch for include intense abdominal pain, persistent vomiting that prevents you from staying hydrated, signs of dehydration like dizziness or dark urine, or any symptom that interferes with your daily life

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Yes, clinical evidence supports long-term safety when monitored by a qualified provider