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With mouse models not being able to accurately recapitulate human neurodevelopmental periods, another translational step could be developing models of haploinsufficiency within NHPssomething that has already been established for the SHANK3 and MECP2 genes within cynomolgus macaques [35, 36]

Patients with family histories of OCD, anxiety, eating disorders, or other compulsive conditions may benefit from genetic insight before committing to semaglutide