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Zeng Y, Yang K, Wang F, Zhou L, Hu Y, Tang M, Tang M et al (2016) The glucagon like peptide 1 analogue, exendin-4, attenuates oxidative stress-induced retinal cell death in early diabetic rats through promoting Sirt1 and Sirt3 expression

doi: 10.1016/j.physbeh.2004.01.006 48 ReidelbergerRDHaverACArneloUSmithDDSchaffertCSPermertJ

Daily options include liraglutide (Victoza, Saxenda), while weekly injectable formulations include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and exenatide extended-release (Bydureon BCise)

However, patients with significant insulin resistance, Type 2 diabetes, or BMI-related comorbidities may require clinical assessment to determine whether pharmaceutical GLP-1 agonists or other interventions provide safer, more effective metabolic control

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