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Standard ice packs can freeze medication if they contact the pen directly, so choose cases with barriers between the cooling element and the medication

Zhang AR, Shi WQ, Liu K, Li XL, Liu MJ, Zhang WH, et al

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(1) TB-500 is a synthetic peptide identical to the 43 amino acid structure of the endogenous thymosin beta-4, studied for its involvement in cellular migration, cytoskeletal organization, and inflammatory signaling