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Redox-sensitive signaling factors as a novel molecular targets for cancer therapy

This enables Cagri to form conserved interactions when bound to CTR and AMYRs, including the inter-peptide contacts that facilitate the formation and stabilisation of the bypass motif and the intramolecular salt bridge (E14 Cagri and R17 Cagri )

An additional mode of communication from the gut to the brain includes the enteric nervous system (ENS) and sensory neurons expressing receptors to TNF-, IL-1 or IL-6 (243), and to 5-HT (244), which is abundantly produced at the gut level (245) (upwards black arrows in Figure 2 )

Lang, N

A., Lima, K