A significant proportion of our cohort used dulaglutide (24%) and exenatide (13%), which are less efficacious for weight loss compared with liraglutide and semaglutide [43]
Juan Manuel Perics has also received personal fees, mainly travel support, from Boehringer-Ingelheim, Madrigal, NovoNordisk, MSD and Novartis outside the submitted work
Common Concerns and Misconceptions Let's address the questions we hear most often about GLP-1 medications for PCOS: "Isn't This Just Another Quick Fix?" Unlike crash diets or symptom-masking approaches, GLP-1 medications address a core biological driver of PCOSinsulin resistance
GLP-1 RAs also shouldnt be taken when theres no likely health benefit
This difference is arbitrary and must be clinically relevant
For example, some GLP-1R agonists primarily activate the insulin secretion signaling pathway, whereas others focus more on promoting insulin sensitivity or inhibiting glucagon secretion (Ma et al., 2020)