A new phenotype in Candida-epithelial cell interaction distinguishes colonization- versus vulvovaginal candidiasis-associated strains
Discontinuation Rates Discontinuation rates due to adverse events in the Phase 2 trial were dose-dependent, ranging from approximately 6% in the 1 mg arm to 16% in the 12 mg arm
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The two strategies act on different points in the same pathway and have distinct mechanistic and pharmacological profiles in the published research
The structure consists of an intracellular segment, a transmembrane domain, and an extracellular segment
Chromatography was performed on a Kinetex 2.6 m HILIC 100 , 100 2.1 mm internal diameter column (Phenomenex), with a constant flow rate of 250 l/min and a solvent gradient from 20% Mobile Phase B (50:45:5, ACN:H 2 O:100 mM AmFm in H 2 O) to 22% B at 5 min, 40% B at 10 min, 60% B at 13 min, 80% B at 15 min, and 99% B at 20 min
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