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Its pathogenesis is not attributable to a single factor but is the result of a complex and dynamic interaction among genetic predispositions, environmental stimuli, and immune dysregulation, each of which contributes to initiating and perpetuating the disease cascade

When we compared the enzymatic activity of both purified recombinant proteins, we observed that GpoA Cys36Ala -His x6 lost the glutathione peroxidase capacity compared with GpoA wt -His x6 (Fig 4B)

With a roughly 5-day half-life, a biweekly schedule creates a real valley before the next shot

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Calculation of encapsulation efficiency After a typical encapsulation experiment, PLGA pellets were collected by centrifugation at 12396 g for 20 minutes using a micro centrifuge (Eppendorf 5418, Hamburg, Germany)