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USA 117 , 3246432475 (2020)

Specifically, HC induced a significant change in 15 proteins (i.e., 9 and 6 up- and down-regulated, respectively) involved in autophagy, including the down-regulation of NPC1 (Nieman-Pick type C) and QSOX1 (quiescin sulfhydryl oxidase 1) and the up-regulation of HMOX1 (heme oxygenase 1) and KDM4A (lysine demethylase 4A)

Osman AM, Telity SA, Telity SA, Damanhouri ZA, Al-Harthy SE, Al-Kreathy HM, et al

The approval was granted 54 days after the request for review was approved, the agency said in a statement

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