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The drugs target the GLP-1 receptor, in which the glucagon-like peptide 1 plays a vital role in glucose metabolism [71]

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The combination of GLP-1R-mediated appetite suppression, GIPR-mediated adipose tissue metabolism, and GCGR-driven energy expenditure makes it one of the most comprehensive research tools for studying multi-pathway obesity biology in a single compound

Role of the circadian clock in the metabolic syndrome and nonalcoholic fatty liver disease