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A 10% water volume error translates directly to a 10% concentration error at every subsequent injection

Older studies often missed this effect because they failed to measure glutathione that travels through the blood bound to proteins

"The Relation of Cytotoxin-Associated Gene A Seropositivity with Vitamin B12 Deficiency in Helicobacter pylori-Positive Patients"

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For patients with unusual weight (such as morbid obesity), it may be helpful to check a phenobarbital level 2 hours after the initial loading dose (to confirm an adequate level was achieved and to calculate V D )

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