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3.1 Porphyromonas gingivalis The pathogenesis of P.g extends far beyond the confines of the oral cavity, establishing a complex Oral-Gut-Systemic Axis that underpins its role in a wide array of chronic diseases

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The transcriptional regulator CREB (cAMP response element binding protein) is a critical regulator of axonal growth and neuronal plasticity that is important for neuroprotection and cognition preservation [54]

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