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Similarly, TRP depletion does not reliably induce depressive symptoms in healthy individuals without a history of MDD [7], and mice genetically depleted of brain 5-HT did not develop depressive-like behavior [8]

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Researchers with Wilson's disease or known copper metabolism disorders should avoid GHK-CU entirely

Additionally, a compound found in extra virgin olive oil has been shown to inhibit TMA formation in vitro , suggesting yet again that dietary context matters (23)