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Moreover, the majority of these technologies remain in the preclinical phase, lacking validation in human clinical trials or demonstration of scalable manufacturing processes

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The transition from the lab to testing in humans is one of the most important steps in drug development

The global prevalence of CKD is approximately 10% and is increasing, driven by rising rates of type 2 diabetes (T2D) and obesity [1, 4]

This broader involvement of lipid peroxidation across various RCD types suggests that it act as a common mediator in these processes, although the precise mechanisms remain to be fully elucidated