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In addition to complex I deficiency, dysfunction of mitochondrial quality control pathwaysspecifically PINK1/Parkin-mediated mitophagyplays a pivotal role

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This trial was registered at ClinicalTrials.gov (NCT05102305, Registration Date: 20-October-2021)

NAC can be used to neutralize the toxic breakdown products of paracetamol inhibits DNA adduct formation

(PubMed) Golzarand M, Mirmiran P, Azizi F