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Likewise, the Womens Health Initiative calcium plus vitamin D (CaD) trial reported no overall reduction in breast cancer incidence but observed a modest reduction in ductal carcinoma in situ (DCIS), suggesting potential long-term preventive effects under sustained supplementation (315)

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This initiation precipitates a multitude of alterations in the cellular milieu, notably the augmentation of mitochondrial biogenesis-a mechanism responsible for the genesis of new mitochondria

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Environ Sci Pollut Res 23:1644816455