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26 Our results represent a remarkably high efficacy, comparable to outcomes observed with other antiobesity drugs, 25 suggesting a need to reassess whether a 5% weight reduction is still an optimal target for obesity treatment

2009;21:978-e78

Pendulum is a team made up of experts in microbiology, biochemistry, medicine and nutrition, including Colleen Cutcliffe Ph.D

New developments, such as dual and triple agonists that target the glucagon, GLP-1, and GIP receptors, promise better results

Any peptide with incorrect sequence or modified residues may have substantially different receptor binding profiles

As the efficacy of insulin may be modulated by several factors including ApoE genotype and sex, targeted treatment may be necessary